Tuesday, April 26, 2022

War: The inhuman cost of medical progress

 

With Ukraine certainties are few.

A family flees a village in Mykolaiv district, Ukraine, 7 April. Photo: AAP.


We cannot predict how far the mass destruction will spread, nor for how long. We cannot confidently assess the chances of a diplomatic fix or even a nuclear escalation. 

Beyond the catastrophic effects of bombs and artillery on human life, this war will have an insidious impact on millions far from the battlefields. 

The shaky public health and clinical care systems in Ukraine, a country that struggled to prosper after the collapse of the Soviet Union, are now being crippled. 

Damage to surgical supplies, electricity, clean water, food, supplementary oxygen, medications, hospital records and IT systems has been so extensive that hospitals and clinics near the front lines have been abandoned, the staff relocated. 

The stress experienced by frontline medical and nursing staff is visible. We see the scenes of heroism, as doctors and health workers continue to care for the sick and injured in those underground shelters. 

Then comes the damage less easy to see — the effect of the sanctions and embargoes imposed on Vladimir Putin's regime.

As a war waged by alternative means, there is no question that they are designed as a response offering less carnage than the West’s direct military involvement. But they carry huge implications for ordinary Russians.


Read more: 


There is also the global issue of food. Across the Middle East and parts of Asia and Africa, some 800 million people depend heavily on Russian and Ukrainian wheat.

And you can throw in the other dynamics. Inflation, an economic illness afflicting those least able to adapt, is expected to spread rapidly in the coming months. 

But there has always been that dark truth when it comes to war. Medicine benefits as a by-product of its horrors. 

The familiar example that comes to mind is the rapid developments in plastic surgery after the First World War, much of it through Dr Harold Gillies, the New Zealand-born otolaryngologist, and his revolutionary use of tubed pedicled flaps.1

A paper published in the New England Journal of Medicine at the beginning of the COVID-19 pandemic, listed just a few other examples.2

The authors (both doctors) referred to George Washington who successfully inoculated his army against smallpox. This helped to demonstrate the value and efficacy of a public health intervention which can be marked as one of medicine's greatest achievements.

There was also the US army physician Dr Walter Reed who elucidated the epidemiology of typhoid and yellow fevers during the Spanish–American War.

Then comes penicillin, another medical wonder. Alexander Fleming’s chance discovery in 1928 that the mould penicillium appeared to kill bacteria was publicised around the world at the time, but then it lingered untapped for a decade. 

It was only in 1941 when the US government responded to the imploring of Oxford researchers Howard Florey and Norman Heatley about what this drug could do, and created a system to produce and deliver it in industrial quantities.

In their paper, the authors described this as an undertaking on the scale of the Manhattan Project.

They add “By D-Day in 1944, there was abundant penicillin for wounded soldiers, and by 1945, both service members overseas and civilians at home had ready access to the drug.

“The requisite scientists, laboratories, and production facilities would never have joined together in peacetime or through private industry alone.”

Other therapies, such as chloroquine and radioisotopes, have similar histories, they say.

The sudden acceleration of medical progress through war usually benefits most those of us who only experience conflict as distant history, read about rather than suffered.

I think of how many lives penicillin has saved — it runs to millions, of course.

But ultimately your heart can’t escape what war does to the individual life. 

The following comes from Sasha, a long-serving health worker with MSF.

He's talking about the Russian attack a few weeks ago on Mariupol, the city where he was born that has been so severely battered.3


Read more from Professor Stephen Leeder: 


“In the beginning, things almost seemed more or less normal, even though we knew that nothing really was normal anymore," he wrote on the MSF's website. 

“But then the bombings started and the world we had known existed no more. 

“Our lives became weaved between the bombs and missiles falling from the sky, destroying everything. We could think of nothing else, and we could feel nothing else. 

“The days of the week stopped to have any meaning, I couldn’t tell whether it was Friday or Saturday, it was all just one long nightmare. My sister tried to keep count of the days, but for me it was all a blur.

“In the first few days, we managed to donate some of MSF’s remaining medical supplies to an emergency department in Mariupol, but [then] the electricity and phone network went down.

“How can one describe one’s home becoming a place of terror? 

“There were new cemeteries all over town, in almost all neighbourhoods. Even in the little yard of the kindergarten near my house, where children should be playing. 

“Each day is like losing your whole life.”

I am grateful to Dr Peter Arnold, OAM, for his editorial assistance and suggestions.


References: 

1.       Cal West Med 1930; 1 May.

2.       N Engl J Med 2020; 29 Apr. 

3.       MSF: Ukraine: how long will this disaster continue?; 24 March 2022

 Published in the Medical Observer 7th April 2022

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